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Anti-Phospho-FoxO3a (Ser253) Antibody (7R176)
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Catalog No. TMAB-10714
Anti-Phospho-FoxO3a (Ser253) Antibody (7R176) is a Rabbit antibody targeting Phospho-FoxO3a (Ser253). Anti-Phospho-FoxO3a (Ser253) Antibody (7R176) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-Phospho-FoxO3a (Ser253) Antibody (7R176)
Anti-Phospho-FoxO3a (Ser253) Antibody (7R176)
😃Good
Catalog No. TMAB-10714
Anti-Phospho-FoxO3a (Ser253) Antibody (7R176) is a Rabbit antibody targeting Phospho-FoxO3a (Ser253). Anti-Phospho-FoxO3a (Ser253) Antibody (7R176) can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-FoxO3a (Ser253) Antibody (7R176) is a Rabbit antibody targeting Phospho-FoxO3a (Ser253). Anti-Phospho-FoxO3a (Ser253) Antibody (7R176) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 7R176 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytosol. Nucleus. Note=Translocates to the nucleus upon oxidative stress and in the absence of survival factors. Tissue Specificity : Ubiquitous. |
| Tissue Specificity | Ubiquitous. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthesized peptide: human FOXO3A around the phosphorylation site of S253 |
| Antigen Species | Human |
| Gene Name | FOXO3 |
| Gene ID | |
| Protein Name | Forkhead box protein O3 |
| Uniprot ID | |
| Function | Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation. |
| Molecular Weight | Theoretical: 71 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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