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Anti-FOXO4 Antibody (2X512)

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Catalog No. TMAC-01557

Anti-FOXO4 Antibody (2X512) is a Rabbit antibody targeting FOXO4. Anti-FOXO4 Antibody (2X512) can be used in WB,IHC.

Anti-FOXO4 Antibody (2X512)

Anti-FOXO4 Antibody (2X512)

😃Good
Catalog No. TMAC-01557
Anti-FOXO4 Antibody (2X512) is a Rabbit antibody targeting FOXO4. Anti-FOXO4 Antibody (2X512) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-FOXO4 Antibody (2X512) is a Rabbit antibody targeting FOXO4. Anti-FOXO4 Antibody (2X512) can be used in WB,IHC.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundFKHR (for forkhead in rhabdomyosarcoma), FKHRL1, and AFX1 are members of a subfamily of the forkhead family of transcription factors. AFX1, also known as FoxO4, is expressed in a wide variety of tissues and, like other FKHR proteins, AFX1 contains a single forkhead domain and serine-proline-rich region, which mediate DNA binding. AFX1-mediated transcriptional activation is regulated by the serine/threonine kinase Akt1, which phosphorylates AFX1 and in turn, sequesters AFX1 in the cytosol, thereby blocking nuclear localization and DNA binding. Genetic mutations in FKHR genes, including the t(2;13) and t(1;3) translocations, are commonly found in alveolar rhabdomyosarcomas. Additionally, the t(x;11) translocation of the AFX1 gene, which involves the fusion of a serine-proline-rich sequence of AFX1 to the carboxy terminus of a truncated MLL, results in acute lymphocytic leukemia.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 54/48 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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