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Anti-ITGA6 Antibody (2Q354)
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Catalog No. TMAH-00644
Alias VLA-6, ITGA 6, Integrin alpha-6, CD49 antigen-like family member F, CD antigen CD49f
Anti-ITGA6 Antibody (2Q354) is an antibody targeting ITGA6. Anti-ITGA6 Antibody (2Q354) can be used in ELISA, IF, FCM.
Anti-ITGA6 Antibody (2Q354)
Anti-ITGA6 Antibody (2Q354)
😃Good
Catalog No. TMAH-00644Alias VLA-6, ITGA 6, Integrin alpha-6, CD49 antigen-like family member F, CD antigen CD49f
Anti-ITGA6 Antibody (2Q354) is an antibody targeting ITGA6. Anti-ITGA6 Antibody (2Q354) can be used in ELISA, IF, FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $209 | 7-10 days | |
| 100 μL | $349 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, IF, FCM Reactivity: Human |
| Alias | VLA-6, ITGA 6, Integrin alpha-6, CD49 antigen-like family member F, CD antigen CD49f |
| Ig Type | Rabbit IgG |
| Clone | 2Q354 |
| Reactivity | Human |
| Verified Activity | 1. Immunofluorescence staining of MCF-7 cell with TMAH-00644 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 536-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). 2. Overlay Peak curve showing Hela cells surface stained with TMAH-00644 (red line) at 1:100. The cells were incubated in 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1ug/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| Application | ELISA, IF, FCM |
| Recommended Dose | IF:1:50-1:200; FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human ITGA6 |
| Antigen Species | Human |
| Gene ID | 3655 |
| Uniprot ID | |
| Biology Area | Developmental biology, Signal transduction, Stem cells |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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