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Anti-ITGA6 Antibody (2Q354)

(Synonyms: VLA-6, ITGA 6, Integrin alpha-6, CD49 antigen-like family member F, CD antigen CD49f) Copy Product Info
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Synonyms: VLA-6, ITGA 6, Integrin alpha-6, CD49 antigen-like family member F, CD antigen CD49f

Catalog No. TMAH-00644 Copy Product Info
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Anti-ITGA6 Antibody (2Q354) is an antibody targeting ITGA6. Anti-ITGA6 Antibody (2Q354) can be used in ELISA,FCM,IF.
Anti-ITGA6 Antibody
(2Q354)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2097-10 days7-10 days
100 μL$3497-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ITGA6 Antibody (2Q354) is an antibody targeting ITGA6. Anti-ITGA6 Antibody (2Q354) can be used in ELISA,FCM,IF.
SynonymsVLA-6, ITGA 6, Integrin alpha-6, CD49 antigen-like family member F, CD antigen CD49f
Ig Type
Rabbit IgG
Clone
2Q354
Reactivity
Human
Application
Recommended Dose
IF:1:50-1:200; FCM:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor.
Tissue SpecificityIntegrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limite
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundIntegrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human ITGA6
Antigen Species
Human
Gene Name
ITGA6
Gene ID
Uniprot ID
Biology Area
Developmental biology, Signal transduction, Stem cells
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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