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Synonyms: VLA-6, ITGA 6, Integrin alpha-6, CD49 antigen-like family member F, CD antigen CD49f
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
| Description | Anti-ITGA6 Antibody (2Q354) is an antibody targeting ITGA6. Anti-ITGA6 Antibody (2Q354) can be used in ELISA,FCM,IF. |
| Synonyms | VLA-6, ITGA 6, Integrin alpha-6, CD49 antigen-like family member F, CD antigen CD49f |
| Ig Type | Rabbit IgG |
| Clone | 2Q354 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF:1:50-1:200; FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. |
| Tissue Specificity | Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limite |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human ITGA6 |
| Antigen Species | Human |
| Gene Name | ITGA6 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Developmental biology, Signal transduction, Stem cells |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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