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Anti-GRK2 Antibody (1Q719)
😃Good
Catalog No. TMAB-06780
Anti-GRK2 Antibody (1Q719) is a Rabbit antibody targeting GRK2. Anti-GRK2 Antibody (1Q719) can be used in WB,FCM,IHC-P,IHC-Fr,IF.
Anti-GRK2 Antibody (1Q719)
Anti-GRK2 Antibody (1Q719)
😃Good
Catalog No. TMAB-06780
Anti-GRK2 Antibody (1Q719) is a Rabbit antibody targeting GRK2. Anti-GRK2 Antibody (1Q719) can be used in WB,FCM,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-GRK2 Antibody (1Q719) is a Rabbit antibody targeting GRK2. Anti-GRK2 Antibody (1Q719) can be used in WB,FCM,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG/Kappa |
| Clone | 1Q719 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1:50-100; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Tissue Specificity | Expressed in peripheral blood leukocytes. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq]. |
| Gene Name | GRK2 |
| Gene ID | |
| Protein Name | beta-adrenergic receptor kinase 1 |
| Function | Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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