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Anti-PA2G4 Antibody (7Z293)

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Catalog No. TMAB-09905

Anti-PA2G4 Antibody (7Z293) is a Rabbit antibody targeting PA2G4. Anti-PA2G4 Antibody (7Z293) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.

Anti-PA2G4 Antibody (7Z293)

Anti-PA2G4 Antibody (7Z293)

😃Good
Catalog No. TMAB-09905
Anti-PA2G4 Antibody (7Z293) is a Rabbit antibody targeting PA2G4. Anti-PA2G4 Antibody (7Z293) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PA2G4 Antibody (7Z293) is a Rabbit antibody targeting PA2G4. Anti-PA2G4 Antibody (7Z293) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.
Ig Type
IgG
Clone
7Z293
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
FCM=1:50-100; ICC/IF=1:50-200; IF=1:50-200; IHC-Fr=1:100-200; IHC-P=1:100-200; IP=1:20-50; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus > nucleolus. Tranlocates to the nucleus upon treatment with HRG.
Tissue SpecificityExpressed in several cell lines tested, including primary and transformed cell lines.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundMay play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing.
Antigen Details
Immunogen
A synthesized peptide: human PA2G4
Antigen Species
Human
Gene Name
PA2G4
Gene ID
Protein Name
Proliferation-associated protein 2G4
Uniprot ID
Function
May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site).
Chemical Properties
Molecular WeightTheoretical: 44 kDa. Actual: 48 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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