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Anti-Her2/ERBB2 Antibody-FITC (5S123)

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Catalog No. TMAY-00035F
Alias erb-b2 receptor tyrosine kinase 2, EGFR2

Anti-Her2/ERBB2 Antibody-FITC (5S123) is a FITC-conjugated Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-FITC (5S123) can be used in FCM.

Anti-Her2/ERBB2 Antibody-FITC (5S123)

Anti-Her2/ERBB2 Antibody-FITC (5S123)

😃Good
Catalog No. TMAY-00035FAlias erb-b2 receptor tyrosine kinase 2, EGFR2
Anti-Her2/ERBB2 Antibody-FITC (5S123) is a FITC-conjugated Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-FITC (5S123) can be used in FCM.
Pack SizePriceAvailabilityQuantity
25 T$80 7-10 days
100 T$176 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Her2/ERBB2 Antibody-FITC (5S123) is a FITC-conjugated Mouse antibody targeting Her2/ERBB2. Anti-Her2/ERBB2 Antibody-FITC (5S123) can be used in FCM.
Aliaserb-b2 receptor tyrosine kinase 2, EGFR2
Ig Type
Monoclonal Mouse IgG1
Clone
5S123
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human Her2/ERBB2 expression on SKBR3. Cells were stained with FITC-conjugated anti-Human Her2/ERBB2. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
FCM
Recommended Dose
10 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis product is a recombinant monoclonal antibody expressed from HEK293 cells and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundHuman epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
FITC
Others Formats
Unconjugated/APC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Human HER2 / ErbB2 protein (TMPY-01137)
Antigen Species
Human
Biology Area
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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