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Anti-KLF4 Antibody (7K615)

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Catalog No. TMAB-08093 Copy Product Info
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Anti-KLF4 Antibody (7K615) is a Rabbit antibody targeting KLF4. Anti-KLF4 Antibody (7K615) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Anti-KLF4 Antibody
(7K615)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4707-10 days7-10 days
200 μL$7557-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-KLF4 Antibody (7K615) is a Rabbit antibody targeting KLF4. Anti-KLF4 Antibody (7K615) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
Clone
7K615
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundKLF4 is a transcription factor that works with Sp1 to activate the Laminin gamma1 chain gene. It binds the CACCC core sequence. KLF4 may be involved in the differentiation of epithelial cells and may also function in the development of the skeleton and kidney. KLF4 also has roles as both an oncogene and a tumor suppressor.
Antigen Details
Immunogen
Recombinant Protein: protein within human KLF4 aa 1-500
Antigen Species
Human
Gene Name
KLF4
Gene ID
Protein Name
Krueppel-like factor 4
Uniprot ID
Function
Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
Chemical Properties
Molecular WeightTheoretical: 56 kDa. Actual: 50 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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