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Anti-HP1 alpha Antibody (5L982)
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Catalog No. TMAB-07265
Anti-HP1 alpha Antibody (5L982) is a Rabbit antibody targeting HP1 alpha. Anti-HP1 alpha Antibody (5L982) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Anti-HP1 alpha Antibody (5L982)
Anti-HP1 alpha Antibody (5L982)
😃Good
Catalog No. TMAB-07265
Anti-HP1 alpha Antibody (5L982) is a Rabbit antibody targeting HP1 alpha. Anti-HP1 alpha Antibody (5L982) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-HP1 alpha Antibody (5L982) is a Rabbit antibody targeting HP1 alpha. Anti-HP1 alpha Antibody (5L982) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM. |
| Ig Type | IgG |
| Clone | 5L982 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; IP: 1:20-50; FCM: 1μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome. Chromosome, centromere. Note=Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphase. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| Immunogen | A synthesized peptide: human CBX5 |
| Antigen Species | Human |
| Gene Name | CBX5 |
| Gene ID | |
| Protein Name | Chromobox protein homolog 5 |
| Uniprot ID | |
| Function | Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| Molecular Weight | Theoretical: 22 kDa. Actual: 22 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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