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Anti-lamin B1 Antibody (5L346)
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Catalog No. TMAB-08200
Anti-lamin B1 Antibody (5L346) is a Rabbit antibody targeting lamin B1. Anti-lamin B1 Antibody (5L346) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Anti-lamin B1 Antibody (5L346)
Anti-lamin B1 Antibody (5L346)
😃Good
Catalog No. TMAB-08200
Anti-lamin B1 Antibody (5L346) is a Rabbit antibody targeting lamin B1. Anti-lamin B1 Antibody (5L346) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-lamin B1 Antibody (5L346) is a Rabbit antibody targeting lamin B1. Anti-lamin B1 Antibody (5L346) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM. |
| Ig Type | IgG |
| Clone | 5L346 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:10000-50000; IHC-P: 1:200-800; IHC-Fr: 1:200-800; ICC/IF: 1:50-200; IF: 1:200-800; FCM: 1μg/Test |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010]. |
| Immunogen | KLH conjugated synthetic peptide: human Lamin B1 |
| Antigen Species | Human |
| Gene Name | LMNB1 |
| Gene ID | |
| Protein Name | Lamin-B1 |
| Uniprot ID | |
| Function | Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. |
| Molecular Weight | Theoretical: 70 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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