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Anti-CHD1L Antibody (9O639) is a Rabbit antibody targeting CHD1L. Anti-CHD1L Antibody (9O639) can be used in WB,ICC/IF,IP,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
| Description | Anti-CHD1L Antibody (9O639) is a Rabbit antibody targeting CHD1L. Anti-CHD1L Antibody (9O639) can be used in WB,ICC/IF,IP,FCM. |
| Ig Type | IgG |
| Clone | 9O639 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Localizes at sites of DNA damage. Probably recruited to DNA damage sites by PARylated PARP1. |
| Tissue Specificity | Frequently overexpressed in hepatomacellular carcinomas. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | ATP-dependent chromatin remodeler that mediates chromatin-remodeling following DNA damage.Recruited to DNA damage sites through interaction with poly-ADP-ribose: specifically recognizes and binds histones that are poly-ADP-ribosylated on serine residues in response to DNA damage. |
| Immunogen | A synthesized peptide: human CHD1L |
| Antigen Species | Human |
| Gene Name | CHD1L |
| Gene ID | |
| Protein Name | Chromodomain-helicase-DNA-binding protein 1-like |
| Uniprot ID | |
| Function | DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding. |
| Molecular Weight | Theoretical: 101 kDa. Actual: 101 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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