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Synonyms: UNQ-9341, UNQ9341, UNQ 9341, HEEE-9341, HEEE9341, HEEE 9341, DNGR-1, DNGR1, DNGR 1, CLEC9A, CD-370, CD370, CD 370, 9830005G06Rik


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $108 | 7-10 days | 7-10 days | |
| 10 µg | $169 | 7-10 days | 7-10 days | |
| 20 µg | $267 | 7-10 days | 7-10 days | |
| 50 µg | $488 | 7-10 days | 7-10 days | |
| 100 µg | $776 | 7-10 days | 7-10 days | |
| 200 µg | $1,230 | 7-10 days | 7-10 days | |
| 500 µg | $2,290 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Anti-CLEC9A Antibody, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human CLEC9A, hFc Tag with the EC50 of 30.9 ng/ml determined by ELISA (QC Test). |
| Description | CLEC9A Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 Cells. The accession number is Q6UXN8. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-hFc (IgG1) |
| Accession Number | Q6UXN8 |
| Construction | Lys57-Val241 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 90% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, 100 mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | UNQ-9341, UNQ9341, UNQ 9341, HEEE-9341, HEEE9341, HEEE 9341, DNGR-1, DNGR1, DNGR 1, CLEC9A, CD-370, CD370, CD 370, 9830005G06Rik |
| Research Background | CLEC9A is a recently discovered C-type lectin receptor involved in sensing necrotic cells. In humans, this receptor is selectively expressed by BDCA3(+) myeloid dendritic cells (mDCs), which have been proposed to be the main human cross-presenting mDCs and may represent the human homologue of murine CD8(+) DCs. In mice, it was demonstrated that antigens delivered with antibodies to CLEC9A are presented by CD8(+) DCs to both CD4(+) and CD8(+) T cells and induce antitumor immunity in a melanoma model. |
| Molecular Weight | 48.5 kDa (Predicted); 55-70 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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