Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) V2

Catalog No. TMPY-00689U

Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q16790.

Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) V2

Catalog No. TMPY-00689U

Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q16790.

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Product Information

Biological Activity	Measured by its esterase activity. The specific activity is > 50 pmol/min/µg (QC Test). Immobilized Human CA9, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-CA9 Antibody, hFc Tag with the EC50 of 7.4ng/ml determined by ELISA (QC Test).
Description	Carbonic Anhydrase 9 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q16790.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q16790
Synonyms	MN,Carbonic Anhydrase IX,CAIX,CA9,CA 9
Construction	Gln38-Asp414
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Molecular Weight	66.91 kDa (Predicted); 70-80 kDa (Due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to the regulation of cancer cell differentiation and mediates tumour-associated genes and signalling pathways, including apoptosis, hypoxia, G2M checkpoint, PI3K/AKR/mTOR signalling and TGF-beta signalling pathways.