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Anti-Aspartate Aminotransferase Antibody (3P649)
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Catalog No. TMAB-02876
Anti-Aspartate Aminotransferase Antibody (3P649) is a Rabbit antibody targeting Aspartate Aminotransferase. Anti-Aspartate Aminotransferase Antibody (3P649) can be used in WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF.
Anti-Aspartate Aminotransferase Antibody (3P649)
Anti-Aspartate Aminotransferase Antibody (3P649)
😃Good
Catalog No. TMAB-02876
Anti-Aspartate Aminotransferase Antibody (3P649) is a Rabbit antibody targeting Aspartate Aminotransferase. Anti-Aspartate Aminotransferase Antibody (3P649) can be used in WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Aspartate Aminotransferase Antibody (3P649) is a Rabbit antibody targeting Aspartate Aminotransferase. Anti-Aspartate Aminotransferase Antibody (3P649) can be used in WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF. |
| Ig Type | IgG |
| Clone | 3P649 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Concentration | 1mg/ml |
| Research Background | Aspartate Aminotransferase [Glutamate oxaloacetate transaminase] is a ubiquitous pyridoxal phosphate-dependent enzyme which exists in both mitochondrial and cytosolic forms. The enzyme plays an important role in amino acid metabolism and in the urea and tricarboxylic acid cycles. The 2 isoenzymes are homodimeric. In liver about 80% of the enzyme activity is mitochondrial in origin, whereas in serum the enzyme activity is largely cytosolic. Although the mitochondrial and soluble forms of GOT are coded by different chromosomes, the 2 show close homology in amino acid sequence and were presumably derived from a common ancestral gene. |
| Immunogen | A synthesized peptide: human GOT1 |
| Antigen Species | Human |
| Gene Name | GOT1 |
| Gene ID | |
| Protein Name | Aspartate aminotransferase, cytoplasmic |
| Uniprot ID | |
| Function | Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. |
| Molecular Weight | Theoretical: 46 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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