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Anti-Olig-2/Oligo2 Antibody (2L225)

😃Good
Catalog No. TMAC-02918
Alias RACK17, PRKCBP2, OLIGO2, Olig2, bHLHe19, BHLHB1

Anti-Olig-2/Oligo2 Antibody (2L225) is a Rabbit antibody targeting Olig-2/Oligo2. Anti-Olig-2/Oligo2 Antibody (2L225) can be used in WB,IHC,ICC/IF.

Anti-Olig-2/Oligo2 Antibody (2L225)

Anti-Olig-2/Oligo2 Antibody (2L225)

😃Good
Catalog No. TMAC-02918Alias RACK17, PRKCBP2, OLIGO2, Olig2, bHLHe19, BHLHB1
Anti-Olig-2/Oligo2 Antibody (2L225) is a Rabbit antibody targeting Olig-2/Oligo2. Anti-Olig-2/Oligo2 Antibody (2L225) can be used in WB,IHC,ICC/IF.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4987-10 days
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Product Introduction

Bioactivity
Description
Anti-Olig-2/Oligo2 Antibody (2L225) is a Rabbit antibody targeting Olig-2/Oligo2. Anti-Olig-2/Oligo2 Antibody (2L225) can be used in WB,IHC,ICC/IF.
AliasRACK17, PRKCBP2, OLIGO2, Olig2, bHLHe19, BHLHB1
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-Olig2 antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-Olig2 antibody. Counter stained with hematoxylin.
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 32 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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