Immobilized Human 4-1BB, His Tag at 1 μg/ml (100 μl/Well) on the plate. Dose response curve for Human 4-1BB Ligand Trimer, hFc Tag with the EC50 of 3.3 ng/ml determined by ELISA.

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q07011.

Human

HEK293 Cells

Tumor necrosis factor receptor superfamily member 9,TNFRSF9,T-cell antigen ILA,T-cell antigen 4-1BB homolog,ILA,CDw137,CD137,4-1BB ligand receptor

Leu24-Gln186

> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC

Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.