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Anti-TRAP Antibody (7N644)

Catalog No. TMAB-13740 Copy Product Info
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Anti-TRAP Antibody (7N644) is a Rabbit antibody targeting TRAP. Anti-TRAP Antibody (7N644) can be used in IHC-P,IHC-Fr,IF.

Anti-TRAP Antibody (7N644)

Copy Product Info
🥰Excellent
Catalog No. TMAB-13740

Anti-TRAP Antibody (7N644) is a Rabbit antibody targeting TRAP. Anti-TRAP Antibody (7N644) can be used in IHC-P,IHC-Fr,IF.

Anti-TRAP Antibody
(7N644)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TRAP Antibody (7N644) is a Rabbit antibody targeting TRAP. Anti-TRAP Antibody (7N644) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
7N644
Reactivity
Human
Verified Activity
1. Western blot analysis of A431 cell lysate. Using TRAP (TMAB-13740) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
2. Paraformaldehyde-fixed, paraffin embedded Human Liver Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TRAP Monoclonal Antibody, Unconjugated (TMAB-13740) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Lung; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TRAP Monoclonal Antibody, Unconjugated (TMAB-13740) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining.
Application
Recommended Dose
IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationLysosome.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundInvolved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.
Antigen Details
Immunogen
A synthesized peptide: human TRAP
Antigen Species
Human
Gene Name
ACP5
Gene ID
Protein Name
Tartrate-resistant acid phosphatase type 5
Uniprot ID
Function
Defects in ACP5 are the cause of spondyloenchondrodysplasia with immune dysregulation (SPENCDI) [MIM:607944]. A disease characterized by vertebral and metaphyseal dysplasia, spasticity with cerebral calcifications, and strong predisposition to autoimmune diseases. The skeletal dysplasia is characterized by radiolucent and irregular spondylar and metaphyseal lesions that represent islands of chondroid tissue within bone. Note=ACP5 inactivating mutations result in a functional excess of phosphorylated osteopontin causing deregulation of osteopontin signaling and consequential autoimmune disease.
Chemical Properties
Molecular WeightTheoretical: 37 kDa. Actual: 35, 42 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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