Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

Anti-IL-36RN/IL-1F5 Antibody (3W888) (Synonyms: RP23-176J12.6, interleukin 36 receptor antagonist, Il1hy1, Il...)

Name: Anti-IL-36RN/IL-1F5 Antibody (3W888)
Brand: TargetMol
SKU: TMAY-00309
Rating: 4.5 (1 reviews)

Catalog No. TMAY-00309 Copy Product Info

🥰Excellent

Anti-IL-36RN/IL-1F5 Antibody (3W888) is a Mouse antibody targeting IL-36RN/IL-1F5. Anti-IL-36RN/IL-1F5 Antibody (3W888) can be used in ELISA.

Anti-IL-36RN/IL-1F5 Antibody (3W888)

Copy Product Info

🥰Excellent

Catalog No. TMAY-00309

Synonyms RP23-176J12.6, interleukin 36 receptor antagonist, Il1hy1, Il-1h3, Fil1δ, Fil1delta, AI413231

Anti-IL-36RN/IL-1F5 Antibody (3W888) is a Mouse antibody targeting IL-36RN/IL-1F5. Anti-IL-36RN/IL-1F5 Antibody (3W888) can be used in ELISA.

Anti-IL-36RN/IL-1F5 Antibody
(3W888)

Pack Size	Price	USA Stock	Global Stock	Quantity
100 μL	$199	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-IL-36RN/IL-1F5 Antibody (3W888) is a Mouse antibody targeting IL-36RN/IL-1F5. Anti-IL-36RN/IL-1F5 Antibody (3W888) can be used in ELISA.
Synonyms	RP23-176J12.6, interleukin 36 receptor antagonist, Il1hy1, Il-1h3, Fil1δ, Fil1delta, AI413231
Ig Type	Mouse IgG1
Clone	3W888
Reactivity	Human
Specificity	Human IL-36RN/IL-1F5
Application	ELISA
Recommended Dose	ELISA: 1:1000-1:2000
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This product is a recombinant monoclonal antibody expressed from HEK293 cells.
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Interleukin-1 family member 5 (IL-1F5), also known as interleukin 36 receptor antagonist (IL36RA), is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). IL-1F5 is a highly and specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin 1 family member 9 (IL1F9). IL-1F5 could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist, and interleukin-1 receptor type I (IL-1R1), which is present in epithelial barriers and takes part in the local inflammatory response. It has been proved that IL-1F5 induces IL-4 mRNA and protein expression in glia in vitro and enhances hippocampal expression of IL-4 following intracerebroventricular injection. The inhibitory effect of IL-1F5 on LPS-induced IL-1β is attenuated in cells from IL-4-defective mice. Experiment results suggest that IL-1F5 mediates anti-inflammatory effects through its ability to induce IL-4 production and that this is a consequence of its interaction with the orphan receptor, single Ig IL-1R-related molecule (SIGIRR)/TIR8, as the effects were not observed in SIGIRR-/- mice. In contrast to its effects in brain tissue, IL-1F5 did not attenuate LPS-induced changes, or up-regulated IL-4 in macrophages or dendritic cells, suggesting that the effect is confined to the brain.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein: Human IL-36RN/IL-1F5 Protein (TMPY-00847)
Antigen Species	Human

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

Calculator

Dilution Calculator
Reconstitution Calculator

Keywords

AI-413231AI 413231

Related Tags: buy Anti-IL-36RN/IL-1F5 Antibody (3W888) | purchase Anti-IL-36RN/IL-1F5 Antibody (3W888) | Anti-IL-36RN/IL-1F5 Antibody (3W888) cost | order Anti-IL-36RN/IL-1F5 Antibody (3W888)