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Anti-PLAUR Antibody (5S385)
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Catalog No. TMAB-11528
Anti-PLAUR Antibody (5S385) is a Rabbit antibody targeting PLAUR. Anti-PLAUR Antibody (5S385) can be used in WB.
Anti-PLAUR Antibody (5S385)
Anti-PLAUR Antibody (5S385)
Copy Product Info😃Good
Catalog No. TMAB-11528
Anti-PLAUR Antibody (5S385) is a Rabbit antibody targeting PLAUR. Anti-PLAUR Antibody (5S385) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-PLAUR Antibody (5S385) is a Rabbit antibody targeting PLAUR. Anti-PLAUR Antibody (5S385) can be used in WB. |
| Ig Type | IgG |
| Clone | 5S385 |
| Reactivity | Human |
| Verified Activity | U-937 (H) cells were treated with or without PMA (200 nM) for 72 h, 25 μg total protein per lane of cell lysates (see on figure) probed with PLAUR monoclonal antibody, unconjugated (TMAB-11528) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB=1:1000-5000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Secreted (Probable). |
| Tissue Specificity | Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol(GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq]. |
| Immunogen | Recombinant Protein: human PLAUR protein |
| Antigen Species | Human |
| Gene Name | PLAUR |
| Gene ID | |
| Protein Name | Urokinase plasminogen activator surface receptor |
| Uniprot ID | |
| Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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