Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-S100B Antibody (7I446)

😃Good
Catalog No. TMAB-12461

Anti-S100B Antibody (7I446) is a Rabbit antibody targeting S100B. Anti-S100B Antibody (7I446) can be used in WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF.

Anti-S100B Antibody (7I446)

Anti-S100B Antibody (7I446)

😃Good
Catalog No. TMAB-12461
Anti-S100B Antibody (7I446) is a Rabbit antibody targeting S100B. Anti-S100B Antibody (7I446) can be used in WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4717-10 days7-10 days
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Product Introduction

Bioactivity
Description
Anti-S100B Antibody (7I446) is a Rabbit antibody targeting S100B. Anti-S100B Antibody (7I446) can be used in WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF.
Ig Type
IgG
Clone
7I446
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; FCM: 1:50-100; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus.
Tissue SpecificityAlthough predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundS100 beta is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Antigen Details
Immunogen
A synthesized peptide: human S100B
Antigen Species
Human
Gene Name
S100B
Gene ID
Protein Name
Protein S100-B
Uniprot ID
Function
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
Chemical Properties
Molecular WeightTheoretical: 10 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-S100B Antibody (7I446) | purchase Anti-S100B Antibody (7I446) | Anti-S100B Antibody (7I446) cost | order Anti-S100B Antibody (7I446) | Anti-S100B Antibody (7I446) molecular weight