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Anti-CTH Antibody (9C506)

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Catalog No. TMAB-04751 Copy Product Info
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Anti-CTH Antibody (9C506) is a Rabbit antibody targeting CTH. Anti-CTH Antibody (9C506) can be used in WB,IP.

Anti-CTH Antibody
(9C506)

Pack SizePriceUSA StockGlobal StockQuantity
25 µL$1497-10 days7-10 days
50 µL$2617-10 days7-10 days
100 µL$4737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CTH Antibody (9C506) is a Rabbit antibody targeting CTH. Anti-CTH Antibody (9C506) can be used in WB,IP.
Ig Type
IgG
Clone
9C506
Reactivity
Human
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with CTH monoclonal antibody, unconjugated (TMAB-04751) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000; IP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundCatalyzes the last step in the transsulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate.
Antigen Details
Immunogen
A synthesized peptide: human Cystathionine gamma lyase
Antigen Species
Human
Gene Name
CTH
Gene ID
Protein Name
Cystathionine gamma-lyase
Uniprot ID
Function
Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into –SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.
Chemical Properties
Molecular WeightTheoretical: 45 kDa. Actual: 43 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-CTH Antibody (9C506) molecular weight