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Anti-IRF2 Antibody (8B64) (Synonyms: IRF2_HUMAN, IRF 2, Interferon regulatory factor 2, DKFZp686F0244)
Catalog No. TMAC-02216 Copy Product Info
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Anti-IRF2 Antibody (8B64) is a Rabbit antibody targeting IRF2. Anti-IRF2 Antibody (8B64) can be used in ICC/IF,WB.
Anti-IRF2 Antibody (8B64)
Copy Product Info🥰Excellent
Catalog No. TMAC-02216
Synonyms IRF2_HUMAN, IRF 2, Interferon regulatory factor 2, DKFZp686F0244
Anti-IRF2 Antibody (8B64) is a Rabbit antibody targeting IRF2. Anti-IRF2 Antibody (8B64) can be used in ICC/IF,WB.
Anti-IRF2 Antibody
(8B64)
(8B64)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Related Conjugates and Formulations
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| Description | Anti-IRF2 Antibody (8B64) is a Rabbit antibody targeting IRF2. Anti-IRF2 Antibody (8B64) can be used in ICC/IF,WB. |
| Synonyms | IRF2_HUMAN, IRF 2, Interferon regulatory factor 2, DKFZp686F0244 |
| Ig Type | IgG |
| Clone | 8B64 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of IRF2 on human lung lysates using anti-IRF2 antibody at 1/1,000 dilution. 2. ICC staining IRF2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining IRF2 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining IRF2 in PANC-1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.     |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-α and β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-α and interferon-β genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3? p48 (a component of the ISGF-3 complex) and IFN consensus sequence-binding protein (ICSBP). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 50 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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