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Anti-NDRG2 Antibody (4K579)
Catalog No. TMAB-09301 Copy Product Info
🥰Excellent
Anti-NDRG2 Antibody (4K579) is a Mouse antibody targeting NDRG2. Anti-NDRG2 Antibody (4K579) can be used in WB,ICC/IF.
Anti-NDRG2 Antibody (4K579)
Copy Product Info🥰Excellent
Catalog No. TMAB-09301
Anti-NDRG2 Antibody (4K579) is a Mouse antibody targeting NDRG2. Anti-NDRG2 Antibody (4K579) can be used in WB,ICC/IF.
Anti-NDRG2 Antibody
(4K579)
(4K579)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-NDRG2 Antibody (4K579) is a Mouse antibody targeting NDRG2. Anti-NDRG2 Antibody (4K579) can be used in WB,ICC/IF. |
| Ig Type | IgG2b/Kappa |
| Clone | 4K579 |
| Reactivity | Human,Mouse (predicted:Rat) |
| Verified Activity | 1. Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1: 2000 Primary ab incubation condition: room temperature 2 h Secondary ab: Goat Anti-Mouse IgG H&L (HRP) Lysate: Mouse brain, Rat heart Protein loading quantity: 20 μg Exposure time: 3 s Predicted MW: 41 kDa Observed MW: 41 kDa 2. Cell line: HepG2 Fixative: 4% Paraformaldehyde Permeabilization: 0.1% TritonX-100 Primary ab dilution: 1:50 Primary incubation condition: 4°C overnight Secondary ab: Goat Anti-Mouse IgG Nuclear counter stain: DAPI (Blue) Comment: Color green is the positive signal for TMAB-09301 |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Note=In neurons, seems to concentrate at axonal growth cone. Perinuclear in neurons. |
| Tissue Specificity | Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level). |
| Construction | Recombinant Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | his gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] |
| Gene Name | NDRG2 |
| Gene ID | |
| Protein Name | Protein NDRG2 |
| Function | Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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