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Anti-N4BP1 Antibody (7Q634)
😃Good
Catalog No. TMAB-09203
Anti-N4BP1 Antibody (7Q634) is a Rabbit antibody targeting N4BP1. Anti-N4BP1 Antibody (7Q634) can be used in WB.
Anti-N4BP1 Antibody (7Q634)
Anti-N4BP1 Antibody (7Q634)
😃Good
Catalog No. TMAB-09203
Anti-N4BP1 Antibody (7Q634) is a Rabbit antibody targeting N4BP1. Anti-N4BP1 Antibody (7Q634) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-N4BP1 Antibody (7Q634) is a Rabbit antibody targeting N4BP1. Anti-N4BP1 Antibody (7Q634) can be used in WB. |
| Ig Type | IgG |
| Clone | 7Q634 |
| Reactivity | Mouse,Rat (predicted:Human) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus; nucleolus. Nucleus; PML body. Primarily localizes to the nucleolus. Also localizes to the PML nuclear bodies, when desumoylated. |
| Tissue Specificity | Detected in heart, lung, brain, liver, skeletal muscle, pancreas, kidney, spleen, testis and ovary. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Potent suppressor of cytokine production that acts as a regulator of innate immune signaling and inflammation.Acts as a key negative regulator of select cytokine and chemokine responses elicited by TRIF-independent Toll-like receptors (TLRs), thereby limiting inflammatory cytokine responses to minor insults. |
| Immunogen | A synthesized peptide: mouse N4BP1 |
| Antigen Species | Mouse |
| Gene Name | N4BP1 |
| Gene ID | |
| Protein Name | NEDD4-binding protein 1 |
| Uniprot ID | |
| Function | Inhibitor of the E3 ubiquitin-protein ligase ITCH. Acts by interacting with the second WW domain of ITCH, leading to compete with ITCH's substrates and impairing ubiquitination of substrates. |
| Molecular Weight | Theoretical: 99 kDa. Actual: 110 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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