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IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant (Active)
(Synonyms: Interleukin-36 alpha, Il36a, IL-1H1, Il1h1, IL-1F6, Il1f6, Il1e, IL-1 epsilon, Fil1e) Copy Product InfoSynonyms: Interleukin-36 alpha, Il36a, IL-1H1, Il1h1, IL-1F6, Il1f6, Il1e, IL-1 epsilon, Fil1e
Catalog No. TMPX-00006 Copy Product Info
IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant (Active) is expressed in E. coli. The accession number is Q9JLA2.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $135 | 7-10 days | 7-10 days | |
| 10 µg | $216 | 7-10 days | 7-10 days | |
| 20 µg | $428 | 7-10 days | 7-10 days | |
| 50 µg | $853 | 7-10 days | 7-10 days | |
| 100 µg | $1,500 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion in murine NIH/3T3 cells is less than 25 ng/ml, corresponding to a specific activity of > 4.0 × 10^4 IU/mg. |
| Description | IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant (Active) is expressed in E. coli. The accession number is Q9JLA2. |
| Species | Mouse |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | Q9JLA2 |
| Amino Acid | RAASPSLRHV QDLSSRVWIL QNNILTAVPR KEQTVPVTIT LLPCQYLDTL ETNRGDPTYM GVQRPMSCLF CTKDGEQPVL QLGEGNIMEM YNKKEPVKAS LFYHKKSGTT STFESAAFPG WFIAVCSKGS CPLILTQELG EIFITDFEMI VVH |
| Construction | Arg8-His160 |
| Protein Purity | > 95% as determined by SDS-PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, 1 mM DTT, 3% trehalose. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water or aqueous buffer containing 0.1 % BSA. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | Interleukin-36 alpha, Il36a, IL-1H1, Il1h1, IL-1F6, Il1f6, Il1e, IL-1 epsilon, Fil1e |
| Research Background | Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases. IL-36α, IL-36β, and IL-36γ (formerly IL-1F6, IL-1F8, and IL-1F9) are IL-1 family members that signal through the IL-1 receptor family members IL-1Rrp2 (IL-1RL2) and IL-1RAcP. IL-36α is mainly found in skin and lymphoid tissues, but also in fetal brain, trachea, stomach and intestine. It is expressed by monocytes, B and T cells. Notably, IL-36 alpha is the only novel IL-1 family member expressed on T-cells. Recombinant murine interleukin-36 alpha contains 153 amino acids residues which is a single non-glycosylated polypeptide. Specifically, mouse IL-36α shares 83 % a.a. sequence identity with rat IL-36α, 54 – 60 % with human, rabbit, equine and bovine IL-36α. |
| Molecular Weight | 17.1 kDa (Predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant (Active) chemical structure | IL-36 alpha/IL-1F6 Protein, Mouse, Recombinant (Active) molecular weight
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