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Anti-CD46 Antibody (1W587)
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Catalog No. TMAB-04008
Anti-CD46 Antibody (1W587) is a Rabbit antibody targeting CD46. Anti-CD46 Antibody (1W587) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Anti-CD46 Antibody (1W587)
Anti-CD46 Antibody (1W587)
😃Good
Catalog No. TMAB-04008
Anti-CD46 Antibody (1W587) is a Rabbit antibody targeting CD46. Anti-CD46 Antibody (1W587) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CD46 Antibody (1W587) is a Rabbit antibody targeting CD46. Anti-CD46 Antibody (1W587) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| Clone | 1W587 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein. Note=Inner acrosomal membrane of spermatozoa. Isoform 2: Secreted (Probable). |
| Tissue Specificity | Present only in testis (at protein level). |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | CD46 is one of the membrane complement regulatory proteins. CD46 possesses C3b-binding and factor I cofactor activities which play important roles in the regulation of the complement activation pathway. CD46 is widely distributed on blood cells, endothelial cells, epithelial cells and tumor cell lines. CD46 exists as many isoforms in a variety of tissues. The antigen has a broad distribution and is present on leukocytes, platelets, endothelial cells, epithelial cells and fibroblasts. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. It is expressed on thymocytes, B cells, monocytes, granulocytes, NK cells, platelets, epithelial and endothelial cells. |
| Immunogen | A synthesized peptide: human CD46 |
| Antigen Species | Human |
| Gene Name | CD46 |
| Gene ID | |
| Protein Name | Membrane cofactor protein |
| Uniprot ID | |
| Function | May be involved in the fusion of the spermatozoa with the oocyte during fertilization. |
| Molecular Weight | Theoretical: 36 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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