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Anti-NHERF1 Antibody (1A168) (Synonyms: Solute carrier family 9 isoform A3 regulatory factor 1, Sodium-hydrogen...)
Catalog No. TMAC-01219 Copy Product Info
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Anti-NHERF1 Antibody (1A168) is a Rabbit antibody targeting NHERF1. Anti-NHERF1 Antibody (1A168) can be used in IHC,WB.
Anti-NHERF1 Antibody (1A168)
Copy Product Info🥰Excellent
Catalog No. TMAC-01219
Synonyms Solute carrier family 9 isoform A3 regulatory factor 1, Sodium-hydrogen exchanger regulatory factor 1, SLC9A3R1, Regulatory cofactor of Na(+)/H(+) exchanger, NHERF-1, NHERF1, NHERF, Na(+)/H(+) exchange regulatory cofactor NHE-RF1, Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50)
Anti-NHERF1 Antibody (1A168) is a Rabbit antibody targeting NHERF1. Anti-NHERF1 Antibody (1A168) can be used in IHC,WB.
Anti-NHERF1 Antibody
(1A168)
(1A168)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-NHERF1 Antibody (1A168) is a Rabbit antibody targeting NHERF1. Anti-NHERF1 Antibody (1A168) can be used in IHC,WB. |
| Synonyms | Solute carrier family 9 isoform A3 regulatory factor 1, Sodium-hydrogen exchanger regulatory factor 1, SLC9A3R1, Regulatory cofactor of Na(+)/H(+) exchanger, NHERF-1, NHERF1, NHERF, Na(+)/H(+) exchange regulatory cofactor NHE-RF1, Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) |
| Ig Type | IgG |
| Clone | 1A168 |
| Reactivity | Human,Rat |
| Verified Activity | 1. Western blot analysis of EBP50 on MCF-7 cells lysates using anti-EBP50 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-EBP50 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-EBP50 antibody. Counter stained with hematoxylin.    |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The Na+/H+ exchange protein (NHE3) functions in transepithelial Na+ absorption and is primarily expressed in the intestinal and renal brush border membrane. NHE3 regulatory factor 1 (NHERF-1) interacts with NHE3 through two PDZ (for PSD-95, Discs-large and ZO-1 homology) domains, which are protein-protein interaction modules that associate with specific carboxy-terminal motifs on target proteins. Also known as EBP50, NHERF-1 facilitates cAMP inhibition of NHE3 to decrease Na+ adsorption. NHERF-1 functions as a scaffold for an essential multiprotein complex of Ezrin and NHE3 for cAMP-mediated phosphorylation and consequent inhibition of NHE3. The amino-terminal PDZ domain regulates the dimerization of NHERF-1 in vivo. G protein-coupled receptor kinase 6A phosphorylates NHERF-1 at Ser 289 via a PDZ domain-mediated interaction. NHERF-2, also known as E3KARP, is a ubiquitously expressed protein which also functions in NHE2 regulation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 50 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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