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Anti-CCR4 Antibody (2Q459)
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Catalog No. TMAH-00156
Anti-CCR4 Antibody (2Q459) is an antibody targeting CCR4. Anti-CCR4 Antibody (2Q459) can be used in ELISA,FCM.
Anti-CCR4 Antibody (2Q459)
Anti-CCR4 Antibody (2Q459)
😃Good
Catalog No. TMAH-00156
Anti-CCR4 Antibody (2Q459) is an antibody targeting CCR4. Anti-CCR4 Antibody (2Q459) can be used in ELISA,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $207 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CCR4 Antibody (2Q459) is an antibody targeting CCR4. Anti-CCR4 Antibody (2Q459) can be used in ELISA,FCM. |
| Ig Type | Human IgG1 |
| Clone | 2Q459 |
| Reactivity | Human |
| Verified Activity | 1. The Binding Activity of CCR4 with Anti-CCR4 Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized CCR4 at 10 μg/mL can bind Anti-CCR4 Recombinant Antibody, the EC50 is 362.3-630.8 ng/mL. 2. Untransfected HEK293 cells surface (green line) and transfected Human CCR4 HEK293 stable cells surface (red line) were stained with anti-CCR4 antibody(2µl/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. |
| Application | |
| Recommended Dose | FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Predominantly expressed in the thymus, in peripheral blood leukocytes, including T-cells, mostly CD4+ cells, and basophils, and in platelets; at lower levels, in the spleen and in monocytes. Detected also in macrophages, IL-2-activated natural killer cell |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CCR4 Protein |
| Antigen Species | Human |
| Gene Name | CCR4 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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