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Anti-CCR4 Antibody (2Q459) is an antibody targeting CCR4. Anti-CCR4 Antibody (2Q459) can be used in ELISA, FC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $207 | 7-10 days | |
100 μL | $349 | 7-10 days |
Description | Anti-CCR4 Antibody (2Q459) is an antibody targeting CCR4. Anti-CCR4 Antibody (2Q459) can be used in ELISA, FC. |
Ig Type | Human IgG1 |
Clone | 2Q459 |
Reactivity | Human |
Verified Activity | 1. The Binding Activity of CCR4 with Anti-CCR4 Recombinant Antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized CCR4 at 10 μg/mL can bind Anti-CCR4 Recombinant Antibody, the EC50 is 362.3-630.8 ng/mL. 2. Untransfected HEK293 cells surface (green line) and transfected Human CCR4 HEK293 stable cells surface (red line) were stained with anti-CCR4 antibody(2µl/1*10^6 cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry. |
Application | ELISA, FC |
Recommended Dose | FC:1:50-1:200. |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Research Background | High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human CCR4 Protein |
Antigen Species | Human |
Gene ID | 1233 |
Uniprot ID | |
Biology Area | Immunology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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