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Anti-CYP1A2 Antibody (9D8)

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Catalog No. TMAB-04871

Anti-CYP1A2 Antibody (9D8) is a Rabbit antibody targeting CYP1A2. Anti-CYP1A2 Antibody (9D8) can be used in WB,ICC/IF,FCM.

Anti-CYP1A2 Antibody (9D8)

Anti-CYP1A2 Antibody (9D8)

😃Good
Catalog No. TMAB-04871
Anti-CYP1A2 Antibody (9D8) is a Rabbit antibody targeting CYP1A2. Anti-CYP1A2 Antibody (9D8) can be used in WB,ICC/IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CYP1A2 Antibody (9D8) is a Rabbit antibody targeting CYP1A2. Anti-CYP1A2 Antibody (9D8) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
Clone
9D8
Reactivity
Human
Application
WB
ICC/IF
FCM
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue SpecificityLiver.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundA cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase).
Antigen Details
Immunogen
A synthesized peptide: human Cytochrome P450 1A2
Antigen Species
Human
Gene Name
CYP1A2
Gene ID
1544
Protein Name
Cytochrome P450 1A2
Uniprot ID
P05177
Function
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
Chemical Properties
Molecular WeightTheoretical: 58 kDa. Actual: 58 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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