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Anti-Sumo2/3 Antibody (4V504)
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Catalog No. TMAB-13273
Anti-Sumo2/3 Antibody (4V504) is a Rabbit antibody targeting Sumo2/3. Anti-Sumo2/3 Antibody (4V504) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P.
Anti-Sumo2/3 Antibody (4V504)
Anti-Sumo2/3 Antibody (4V504)
😃Good
Catalog No. TMAB-13273
Anti-Sumo2/3 Antibody (4V504) is a Rabbit antibody targeting Sumo2/3. Anti-Sumo2/3 Antibody (4V504) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Sumo2/3 Antibody (4V504) is a Rabbit antibody targeting Sumo2/3. Anti-Sumo2/3 Antibody (4V504) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P. |
| Ig Type | IgG |
| Clone | 4V504 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | FCM=1:50-100; ICC/IF=1:50-200; IF=1:50-200; IHC-Fr=1:50-200; IHC-P=1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Nucleus, PML body. |
| Tissue Specificity | Broadly expressed. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Small ubiquitin-related modifier 1, 2 and 3 (SUMO-1, -2 and -3) are members of the ubiquitin-like protein family. The covalent attachment of the SUMO-1, -2 or -3 (SUMOylation) to target proteins is analogous to ubiquitination. This post-translational modification is a reversible, multi-step process that is initiated by cleaving a precursor protein to a mature protein. |
| Immunogen | A synthesized peptide: human Sumo 2 |
| Antigen Species | Human |
| Gene Name | SUMO2 |
| Gene ID | |
| Protein Name | Small ubiquitin-related modifier 2 |
| Uniprot ID | |
| Function | Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. |
| Molecular Weight | Theoretical: 11, 12 kDa. Actual: 16 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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