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Anti-PTPN1/2 Antibody (4Q525)

Catalog No. TMAB-11923 Copy Product Info
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Anti-PTPN1/2 Antibody (4Q525) is a Rabbit antibody targeting PTPN1/2. Anti-PTPN1/2 Antibody (4Q525) can be used in WB,IP,FCM.

Anti-PTPN1/2 Antibody (4Q525)

Copy Product Info
🥰Excellent
Catalog No. TMAB-11923

Anti-PTPN1/2 Antibody (4Q525) is a Rabbit antibody targeting PTPN1/2. Anti-PTPN1/2 Antibody (4Q525) can be used in WB,IP,FCM.

Anti-PTPN1/2 Antibody
(4Q525)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1507-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PTPN1/2 Antibody (4Q525) is a Rabbit antibody targeting PTPN1/2. Anti-PTPN1/2 Antibody (4Q525) can be used in WB,IP,FCM.
Ig Type
IgG
Clone
4Q525
Reactivity
Human,Mouse
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with TMAB-11923 monoclonal antibody, unconjugated (TMAB-11923) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000; IP: 1:20-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Interacts with EPHA3 at the cell membrane.
Tissue SpecificityMost abundant in testis. Also found in kidney, spleen, muscle, liver, heart and brain.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundTyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades.
Antigen Details
Immunogen
A synthesized peptide: human PTPN1
Antigen Species
Human
Gene Name
PTPN1
Gene ID
Protein Name
Tyrosine-protein phosphatase non-receptor type 1
Uniprot ID
Function
Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion
Chemical Properties
Molecular WeightTheoretical: 50, 48 kDa. Actual: 40-48 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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