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Anti-PTPN1/2 Antibody (4Q525) is a Rabbit antibody targeting PTPN1/2. Anti-PTPN1/2 Antibody (4Q525) can be used in WB,IP,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
| Description | Anti-PTPN1/2 Antibody (4Q525) is a Rabbit antibody targeting PTPN1/2. Anti-PTPN1/2 Antibody (4Q525) can be used in WB,IP,FCM. |
| Ig Type | IgG |
| Clone | 4Q525 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000; IP: 1:20-50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Interacts with EPHA3 at the cell membrane. |
| Tissue Specificity | Most abundant in testis. Also found in kidney, spleen, muscle, liver, heart and brain. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. |
| Immunogen | A synthesized peptide: human PTPN1 |
| Antigen Species | Human |
| Gene Name | PTPN1 |
| Gene ID | |
| Protein Name | Tyrosine-protein phosphatase non-receptor type 1 |
| Uniprot ID | |
| Function | Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion |
| Molecular Weight | Theoretical: 50, 48 kDa. Actual: 40-48 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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