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Synonyms: MAC2GAL3, Mac-2, LGALS3, LGALS2, Lectin L-29, L31, L29, GALIG, Galectin3, GALBPCBP35, galactin-3, Gal-3, GAL3, CBP35, AGE-R3
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
| Description | Anti-LGALS3 Antibody (9L292) is an antibody targeting LGALS3. Anti-LGALS3 Antibody (9L292) can be used in ELISA,IF,IHC,IP,WB. |
| Synonyms | MAC2GAL3, Mac-2, LGALS3, LGALS2, Lectin L-29, L31, L29, GALIG, Galectin3, GALBPCBP35, galactin-3, Gal-3, GAL3, CBP35, AGE-R3 |
| Ig Type | Rabbit IgG |
| Clone | 9L292 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200; IF:1:20-1:200; IP:1:200-1:1000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Nucleus. Secreted. |
| Tissue Specificity | A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Galectin 3 |
| Antigen Species | Human |
| Gene Name | LGALS3 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Neuroscience, Cell biology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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