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Anti-SUV39H2 Antibody (8R663)
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Catalog No. TMAC-03923
Anti-SUV39H2 Antibody (8R663) is a Rabbit antibody targeting SUV39H2. Anti-SUV39H2 Antibody (8R663) can be used in WB,IHC,IP.
Anti-SUV39H2 Antibody (8R663)
Anti-SUV39H2 Antibody (8R663)
😃Good
Catalog No. TMAC-03923
Anti-SUV39H2 Antibody (8R663) is a Rabbit antibody targeting SUV39H2. Anti-SUV39H2 Antibody (8R663) can be used in WB,IHC,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Chemical Properties
| Description | Anti-SUV39H2 Antibody (8R663) is a Rabbit antibody targeting SUV39H2. Anti-SUV39H2 Antibody (8R663) can be used in WB,IHC,IP. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; IP: 1:10-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher-order chromatin organization during spermatogenesis. Recruited by the large PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1, contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation. |
| Conjucates | Unconjugated |
| Immunogen | A synthesized peptide: within Human SUV39H2 aa 350 to the C-terminus |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 40/47 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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