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Anti-SUV39H2 Antibody (8R663) (Synonyms: SUV92_HUMAN, Suv39h2, Suppressor of variegation 3-9 homolog 2, Suppr...)

Catalog No. TMAC-03923 Copy Product Info
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Anti-SUV39H2 Antibody (8R663) is a Rabbit antibody targeting SUV39H2. Anti-SUV39H2 Antibody (8R663) can be used in IHC,IP,WB.

Anti-SUV39H2 Antibody (8R663)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03923
Synonyms SUV92_HUMAN, Suv39h2, Suppressor of variegation 3-9 homolog 2, Suppressor of variegation 3 9 homolog 2, Su(var)3-9 homolog 2, Su(var)3 9 homolog 2, Su(var)3 9 Drosophila homolog of 2, sSuppressor of variegation 3 9 homolog 2 (Drosophila), Lysine N-methyltransferase 1B, Lysine N methyltransferase 1B, KMT1B, Histone-lysine N-methyltransferase SUV39H2, Histone lysine N methyltransferase SUV39H2, Histone lysine N methyltransferase H3 lysine 9 specific 2, Histone H3-K9 methyltransferase 2, Histone H3 K9 methyltransferase 2, H3-K9-HMTase 2, H3 K9 HMTase 2, FLJ23414

Anti-SUV39H2 Antibody (8R663) is a Rabbit antibody targeting SUV39H2. Anti-SUV39H2 Antibody (8R663) can be used in IHC,IP,WB.

Anti-SUV39H2 Antibody
(8R663)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SUV39H2 Antibody (8R663) is a Rabbit antibody targeting SUV39H2. Anti-SUV39H2 Antibody (8R663) can be used in IHC,IP,WB.
SynonymsSUV92_HUMAN, Suv39h2, Suppressor of variegation 3-9 homolog 2, Suppressor of variegation 3 9 homolog 2, Su(var)3-9 homolog 2, Su(var)3 9 homolog 2, Su(var)3 9 Drosophila homolog of 2, sSuppressor of variegation 3 9 homolog 2 (Drosophila), Lysine N-methyltransferase 1B, Lysine N methyltransferase 1B, KMT1B, Histone-lysine N-methyltransferase SUV39H2, Histone lysine N methyltransferase SUV39H2, Histone lysine N methyltransferase H3 lysine 9 specific 2, Histone H3-K9 methyltransferase 2, Histone H3 K9 methyltransferase 2, H3-K9-HMTase 2, H3 K9 HMTase 2, FLJ23414
Ig Type
IgG
Clone
8R663
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of SUV39H2 on SiHa cell (1) and A549 cell (2) lysate using anti- SUV39H2 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti- SUV39H2 antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; IP: 1:10-50
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundHistone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher-order chromatin organization during spermatogenesis. Recruited by the large PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1, contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthesized peptide: within Human SUV39H2 aa 350 to the C-terminus
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 40/47 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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