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Anti-SUV39H2 Antibody (8R663)

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Catalog No. TMAC-03923

Anti-SUV39H2 Antibody (8R663) is a Rabbit antibody targeting SUV39H2. Anti-SUV39H2 Antibody (8R663) can be used in WB,IHC,IP.

Anti-SUV39H2 Antibody (8R663)

Anti-SUV39H2 Antibody (8R663)

😃Good
Catalog No. TMAC-03923
Anti-SUV39H2 Antibody (8R663) is a Rabbit antibody targeting SUV39H2. Anti-SUV39H2 Antibody (8R663) can be used in WB,IHC,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-SUV39H2 Antibody (8R663) is a Rabbit antibody targeting SUV39H2. Anti-SUV39H2 Antibody (8R663) can be used in WB,IHC,IP.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; IP: 1:10-50
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundHistone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher-order chromatin organization during spermatogenesis. Recruited by the large PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1, contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthesized peptide: within Human SUV39H2 aa 350 to the C-terminus
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 40/47 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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