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Anti-Glutaminase Antibody (8G424) (Synonyms: L-glutamine amidohydrolase, KIAA0838, K-glutaminase, KGA, Gluta...)
Catalog No. TMAC-01686 Copy Product Info
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Anti-Glutaminase Antibody (8G424) is a Rabbit antibody targeting Glutaminase. Anti-Glutaminase Antibody (8G424) can be used in ICC/IF,IHC,WB.
Anti-Glutaminase Antibody (8G424)
Copy Product Info🥰Excellent
Catalog No. TMAC-01686
Synonyms L-glutamine amidohydrolase, KIAA0838, K-glutaminase, KGA, Glutaminase kidney isoform, mitochondrial, GLSK, GLS, GDPAG, GAM, GAC, EIEE71, EC:3.5.1.2, DEE71, CASGID, AAD20
Anti-Glutaminase Antibody (8G424) is a Rabbit antibody targeting Glutaminase. Anti-Glutaminase Antibody (8G424) can be used in ICC/IF,IHC,WB.
Anti-Glutaminase Antibody
(8G424)
(8G424)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Glutaminase Antibody (8G424) is a Rabbit antibody targeting Glutaminase. Anti-Glutaminase Antibody (8G424) can be used in ICC/IF,IHC,WB. |
| Synonyms | L-glutamine amidohydrolase, KIAA0838, K-glutaminase, KGA, Glutaminase kidney isoform, mitochondrial, GLSK, GLS, GDPAG, GAM, GAC, EIEE71, EC:3.5.1.2, DEE71, CASGID, AAD20 |
| Ig Type | IgG |
| Clone | 8G424 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of Glutaminase on different lysates using anti-Glutaminase antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: 293. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Glutaminase antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Glutaminase antibody. Counter stained with hematoxylin. 4. ICC staining Glutaminase in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining Glutaminase in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.      |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Glutamine is an important molecule involved in several cellular functions, including nitrogen and carbon transport, hepatic urea synthesis, renal ammoniagenesis, and gluconeogenesis. Glutamine is catabolized by either the liver-type (LGA) or kidney-type (KGA) glutaminase. KGA is mitochondrial specific protein whose expression in kidney is increased during metabolic acidosis. This process is mediated by an 8-base AU-sequence in KGA that functions as a pH-response element. The human KGA gene maps to chromosome 2, and produces three isoforms, designated KGA, GAC, and GAM, by alternative splicing. KGA is synthesized as a cytosolic protein that is transported to the mitochondria as an intermediate protein, and is further cleaved into the KGA isoform and the GAC isoform. The processing of the GAM isoform is unclear. The KGA isoform is abundant in brain and kidney, while the GAC isoform is principally expressed in cardiac muscle and pancreas. The GAM isoform is solely expressed in cardiac and skeletal muscle. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 65 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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