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Anti-Cubilin Antibody (8J369)
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Catalog No. TMAC-01017
Alias MGA1, megaloblastic anemia 1, Intrinsic factor-vitamin B12 receptor, Intrinsic factor-cobalamin receptor, intrinsic factor B12-receptor, Intestinal intrinsic factor receptor, IFCR, CUBN_HUMAN, Cubn, Cubilin precursor, cubilin (intrinsic factor-cobalamin receptor), Cubilin, 460 kDa receptor
Anti-Cubilin Antibody (8J369) is a Rabbit antibody targeting Cubilin. Anti-Cubilin Antibody (8J369) can be used in WB,IHC.
Anti-Cubilin Antibody (8J369)
Anti-Cubilin Antibody (8J369)
😃Good
Catalog No. TMAC-01017Alias MGA1, megaloblastic anemia 1, Intrinsic factor-vitamin B12 receptor, Intrinsic factor-cobalamin receptor, intrinsic factor B12-receptor, Intestinal intrinsic factor receptor, IFCR, CUBN_HUMAN, Cubn, Cubilin precursor, cubilin (intrinsic factor-cobalamin receptor), Cubilin, 460 kDa receptor
Anti-Cubilin Antibody (8J369) is a Rabbit antibody targeting Cubilin. Anti-Cubilin Antibody (8J369) can be used in WB,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Cubilin Antibody (8J369) is a Rabbit antibody targeting Cubilin. Anti-Cubilin Antibody (8J369) can be used in WB,IHC. |
| Synonyms | MGA1, megaloblastic anemia 1, Intrinsic factor-vitamin B12 receptor, Intrinsic factor-cobalamin receptor, intrinsic factor B12-receptor, Intestinal intrinsic factor receptor, IFCR, CUBN_HUMAN, Cubn, Cubilin precursor, cubilin (intrinsic factor-cobalamin receptor), Cubilin, 460 kDa receptor |
| Ig Type | IgG |
| Clone | 8J369 |
| Reactivity | Human |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Cubilin antibody. Counter stained with hematoxylin. |
| Application | |
| Recommended Dose | WB: 1:500; IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 399 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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