Anti-BTC Antibody (7D630)

Name: Anti-BTC Antibody (7D630)
Brand: TargetMol
SKU: TMAB-03244
Rating: 4.5 (1 reviews)

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Catalog No. TMAB-03244

Anti-BTC Antibody (7D630) is a Mouse antibody targeting BTC. Anti-BTC Antibody (7D630) can be used in WB,ICC/IF.

Anti-BTC Antibody (7D630)

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Catalog No. TMAB-03244

Anti-BTC Antibody (7D630) is a Mouse antibody targeting BTC. Anti-BTC Antibody (7D630) can be used in WB,ICC/IF.

Pack Size	Price	USA Warehouse	Global Warehouse
25 μL	$148	7-10 days	7-10 days
50 μL	$261	7-10 days	7-10 days
100 μL	$472	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-BTC Antibody (7D630) is a Mouse antibody targeting BTC. Anti-BTC Antibody (7D630) can be used in WB,ICC/IF.
Ig Type	IgG1, Kappa
Clone	7D630
Reactivity	Human
Verified Activity	1. Cell line: PC-3 Fixative: 4% Paraformaldehyde Permeabilization: 0.1% TritonX-100 Primary ab dilution: 1:50 Primary incubation condition: 4°C overnight Secondary ab: Goat Anti-Mouse IgG Nuclear counter stain: DAPI (Blue) Comment: Color green is the positive signal for TMAB-03244 2. Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:1000 Primary ab incubation condition: room temperature 2 h Secondary ab: Goat Anti-Mouse IgG H&L (HRP) Lysate: Panc-1, PC-3, T47D Protein loading quantity: 20 μg Exposure time: 30 s Predicted MW: 20 kDa Observed MW: 20 kDa
Application	WB ICC/IF
Recommended Dose	WB: 1:500-2000; ICC/IF: 1:50-200
Antibody Type	Monoclonal
Host Species	Mouse
Subcellular Localization	Cell membrane and Secreted > extracellular space.
Tissue Specificity	Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine.
Construction	Recombinant Antibody
Purification	Protein G purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1mg/ml
Research Background	Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, was originally identified as a growth-promoting factor in the conditioned medium of a mouse pancreatic-cell carcinoma (insulinoma) cell line and has since been identified in humans. BTC is synthesized as a large transmembrane precursor molecule that can be cleaved proteolytically to release the soluble form of BTC or function as membrane-anchored growth factors in juxtacrine signaling. BTC, in addition to stimulating homodimers of ErbB-1 and ErbB-4, is capable of binding and activating all possible combinations of heterodimeric ErbB receptors including the oncogenic ErbB-2/ErbB-3 complex. BTC is also expressed in some human malignancies and may have an important role in tumor growth progression.

Antigen Details

Gene Name	BTC
Gene ID	685
Protein Name	Probetacellulin
Function	Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors.

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
Transport	Shipping with blue ice.