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Anti-TEAD1 Antibody (6X620)

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Catalog No. TMAB-13444 Copy Product Info
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Anti-TEAD1 Antibody (6X620) is a Rabbit antibody targeting TEAD1. Anti-TEAD1 Antibody (6X620) can be used in WB,IHC-P,IHC-Fr,IF,IP.
Anti-TEAD1 Antibody
(6X620)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TEAD1 Antibody (6X620) is a Rabbit antibody targeting TEAD1. Anti-TEAD1 Antibody (6X620) can be used in WB,IHC-P,IHC-Fr,IF,IP.
Ig Type
IgG
Clone
6X620
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; IP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
Tissue SpecificityPreferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundTranscription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
Antigen Details
Immunogen
A synthesized peptide: human TEAD1
Antigen Species
Human
Gene Name
TEAD1
Gene ID
Protein Name
Transcriptional enhancer factor TEF-1
Uniprot ID
Function
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.
Chemical Properties
Molecular WeightTheoretical: 48 kDa. Actual: 48-52 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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