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Nitrogen-15 Labeled Compounds

Nitrogen-15 labeled compounds refer to compounds that are labeled with nitrogen-15, an isotope of nitrogen. Nitrogen-15 labeled compounds have been widely used in agriculture, medicine, biochemistry and other fields. For example, nitrogen-15 labeled nitrogen fertilizers can help scientists study the transformation, absorption and utilization of nitrogen fertilizers in the soil, thereby optimizing the application method of nitrogen fertilizers and increasing crop yields. They can also be used to study the metabolic process of drugs in the human body and the pathogenesis of diseases.

L-Lysine-13C6-15N2 Hydrochloride
TMIJ-03801200447-00-2
L-Lysine-13C6-15N2 Hydrochloride is L-Lysine hydrochloride labeled with 13C and 15N isotopes. L-Lysine hydrochloride is an essential amino acid for humans and a common food additive. It stimulates the secretion of pepsin and gastric acid, enhances gastric juice secretion, and promotes growth and development in children.
  • $40
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L-Phenylalanine-15N
L-Phenylalanine-15N, (S)-2-Amino-3-phenylpropionic acid-15N
T4037629700-34-3
L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) is the 15N-labeled L-Phenylalanine. L-Phenylalanine is an essential amino acid isolated from Escherichia coli . L-Phenylalanine is a α2δ subunit of voltage-dependent Ca + channels antagonist with a K i of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) ( K B of 573 μM ) and non-NMDARs , respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.
  • $40
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Riluzole-13C,15N2
PK 26124-13C,15N2
T376081215552-03-6
Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole. Riluzole is a glutamate antagonist with anticonvulsant activity, inhibiting GABA reuptake and used in ALS research.
  • $1,230
35 days
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Roxadustat-13C-15N
TMIH-0506
Roxadustat-13C-15N is 13C and 15N labeled Roxadustat.
  • $685
7-10 days
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5-Fluorouracil-13C,15N2
5-Fluorouracil-13C,15N2
T368951189423-58-2
5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.
  • $838
35 days
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Liraglutide-13C5,15N TFA
TMID-0810
Liraglutide-13C5,15N (tetraTFA) is a version of Liraglutide labeled with 13C and 15N isotopes. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which is clinically used for the treatment of type 2 diabetes.
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Guanosine-13C10,15N5
TMID-0804202406-81-3
Guanosine-13C10,15N5 is a version of Guanosine labeled with isotopes 13C and 15N. Guanosine (DL-Guanosine) is a type of nucleoside, consisting of guanine attached to a ribose ring through a β-N9-glycosidic bond. It has activity against HSV.
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Allopurinol-13C,15N2
TMID-0665
Allopurinol-13C,15N2 is an isotopically labeled form of Allopurinol with Carbon-13 and Nitrogen-15. Allopurinol is an effective oral xanthine oxidase inhibitor with an IC50 value range of 0.2-50 μM, used in the study of hyperuricemia and gout. It reduces the expression of HIF-1α and HIF-2α proteins and exhibits antidepressant and antinociceptive properties. Additionally, Allopurinol has anti-leishmanial effects.
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Cytidine 5′-monophosphate-13C9,15N3 dilithium
TMID-03922483830-57-3
Cytidine 5′-monophosphate-13C9,15N3(5'-Cytidylic acid-13C9,15N3dilithium; 5'-CMP-13C9,15N3) dilithium is the isotopically labeled form of cytidine 5'-monophosphate with carbon-13 and nitrogen-15. Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide that serves as a monomer in RNA, and it comprises a cytosine base, a ribose sugar, and a phosphate group.
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L-Alanine-13C2,15N
TMID-1052312623-85-1
L-Alanine-13C2,15N is an isotopically labeled form of L-Alanine, marked with 13C and 15N. L-Alanine is a non-essential amino acid involved in carbohydrate and acid metabolism, boosts the immune system, and provides energy to muscle tissues, the brain, and the central nervous system.
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Hypoxanthine-15N4
TMID-062277910-30-6
Hypoxanthine-15N4 is the 15N-labeled form of Hypoxanthine. This compound is a purine derivative and serves as a potential free radical generator, as well as an indicator of hypoxia.
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Vadadustat-13C2-15N
TMIH-0591
Vadadustat-13C2-15N is 13C and 15N labeled Vadadustat. Vadadustat has a CAS number of 1000025-07-9. Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.
  • $857
7-10 days
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Pantothenic acid-13C3,15N hemicalcium
TMID-0344356786-94-2
Pantothenic acid-13C3,15N (hemicalcium) is a version of D-Pantothenic acid labeled with 13C and 15N isotopes. D-Pantothenic acid is an essential micronutrient, serving as a precursor to coenzyme A (CoA). It plays a crucial role in numerous biological processes, including the regulation of carbohydrate, lipid, protein, and nucleic acid metabolism.
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L-Aspartic acid-13C4,15N
TMID-0372202468-27-7
L-Aspartic acid-13C4,15N is an isotopically labeled form of L-aspartic acid, containing both 13C and 15N. L-Aspartic acid is an amino acid recognized as a precursor active molecule for targeted molecular delivery within the colon.
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L-Arginine-13C6,15N4,d7 hydrochloride
TMID-07512483829-29-2
L-Arginine-13C6,15N4,d7 (hydrochloride) is an L-Arginine hydrochloride compound labeled with 13C, 15N, and deuterium. This compound, known as L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride), serves as a nitrogen donor for nitric oxide synthesis and acts as a vasodilator.
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L-Valine-13C5-15N
TMIJ-0381202407-30-5
L-Valine-13C5-15N is the 13C and 15N labeled compound of L-Valine. L-Valine has a CAS number of 72-18-4. A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
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20 days
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