Glypican 3/GPC3 Protein, Human, Recombinant (His) V2

Catalog No. TMPY-01283U

Glypican 3/GPC3 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P51654-1.

Glypican 3/GPC3 Protein, Human, Recombinant (His) V2

Catalog No. TMPY-01283U

Glypican 3/GPC3 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P51654-1.

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Product Information

Biological Activity	Immobilized Human GPC3, His Tag at 0.5 μg/ml (100 μl/Well). Dose response curve for Anti-GPC3 Antibody, hFc Tag with the EC50 of 4.7 ng/ml determined by ELISA.
Description	Glypican 3/GPC3 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P51654-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P51654-1
Synonyms	SGBS1,SGBS,SGB,SDYS,OCI-5,MXR7,GTR2-2,Glypican 3,DGSX
Construction	Gln25-His559
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	61.6 kDa (Predicted); 42 kDa, 70-115 kDa (Due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several therapeutic anti-GPC3 antibodies have been developed.