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Anti-SARA Antibody (3N387)

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Catalog No. TMAB-12504

Anti-SARA Antibody (3N387) is a Rabbit antibody targeting SARA. Anti-SARA Antibody (3N387) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-SARA Antibody (3N387)

Anti-SARA Antibody (3N387)

😃Good
Catalog No. TMAB-12504
Anti-SARA Antibody (3N387) is a Rabbit antibody targeting SARA. Anti-SARA Antibody (3N387) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-SARA Antibody (3N387) is a Rabbit antibody targeting SARA. Anti-SARA Antibody (3N387) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
3N387
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Early endosome membrane.
Tissue SpecificityUbiquitous. In the brain found primarily in the cerebrovascular smooth muscle cells and reactive astrocytes.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundEarly endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex.
Antigen Details
Immunogen
A synthesized peptide: human SARA
Antigen Species
Human
Gene Name
ZFYVE9
Gene ID
Protein Name
Zinc finger FYVE domain-containing protein 9
Uniprot ID
Function
Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.
Chemical Properties
Molecular WeightTheoretical: 156 kDa. Actual: 180 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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