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Anti-CDC25B Antibody (1T844)
🥰Excellent
Catalog No. TMAB-04118
Antibody Type: Recombinant Rabbit Monoclonal
Application: WB,IP,FCM
Reactivity: Human,Mouse
Anti-CDC25B Antibody (1T844)
Anti-CDC25B Antibody (1T844)
🥰Excellent
Catalog No. TMAB-04118
Antibody Type: Recombinant Rabbit Monoclonal
Application: WB,IP,FCM
Reactivity: Human,Mouse
Application: WB,IP,FCM
Reactivity: Human,Mouse
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CDC25B Antibody (1T844) is a Rabbit antibody targeting CDC25B. Anti-CDC25B Antibody (1T844) can be used in WB,IP,FCM. |
| Ig Type | IgG |
| Clone | 1T844 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000; IP: 1:20-50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. |
| Immunogen | A synthesized peptide: human CDC25B |
| Antigen Species | Human |
| Gene Name | CDC25B |
| Gene ID | |
| Protein Name | M-phase inducer phosphatase 2 |
| Uniprot ID | |
| Function | Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity. |
| Molecular Weight | Theoretical: 65 kDa. Actual: 64 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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