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Neurotrophin 3 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P20783.

| Pack Size | Price | Availability | Quantity | 
|---|
| Biological Activity | Immobilized  Human AXL-His at 10 μg/ml (100 μl/well) can bind Human GAS6-His*.*: Biotinylated by NHS-biotin prior to testing The ED50 of Recombinant Human GAS6-His* is 0.04466 ug/ml. (Regularly tested) | 
| Description | Neurotrophin 3 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P20783. | 
| Species | Human | 
| Expression System | E. coli | 
| Tag | Tag Free | 
| Accession Number | P20783 | 
| Synonyms | NT-3,NT3,NGF-2,NGF2,neurotrophin 3,HDNF | 
| Construction | Tyr139-Thr257 | 
| Protein Purity | > 95% as determined by SDS-PAGE | 
| Molecular Weight | 13.6 kDa (Predicted); 14 kDa (Reducing conditions) | 
| Endotoxin | < 0.01 EU/μg of the protein as determined by the LAL method. | 
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2. | 
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. | 
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. | 
| Research Background | Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems. | 

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