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Anti-CD38 Antibody (1X483)

Catalog No. TMAB-03966 Copy Product Info
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Anti-CD38 Antibody (1X483) is a Mouse antibody targeting CD38. Anti-CD38 Antibody (1X483) can be used in ICC/IF,FCM.

Anti-CD38 Antibody (1X483)

Copy Product Info
🥰Excellent
Catalog No. TMAB-03966

Anti-CD38 Antibody (1X483) is a Mouse antibody targeting CD38. Anti-CD38 Antibody (1X483) can be used in ICC/IF,FCM.

Anti-CD38 Antibody
(1X483)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1517-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD38 Antibody (1X483) is a Mouse antibody targeting CD38. Anti-CD38 Antibody (1X483) can be used in ICC/IF,FCM.
Ig Type
IgG2a, Kappa
Clone
1X483
Reactivity
Human
Verified Activity
1. Cell line: Raji
Fixative: Unfixed
Permeabilization: None
Primary ab dilution: 1:100
Primary incubation condition: 30 min at room temperature
Unlabelled control: The cell without incubation with primary antibody (Black line).
Isotype control: Mouse monoclonal IgG (Blue line).
Comment: Line red is the positive signal for TMAB-03966
2. Cell line: Ramos
Fixative: 4% Paraformaldehyde
Permeabilization: 0.1% TritonX-100
Primary ab dilution: 1:50
Primary incubation condition: 45 mins at room temperature
Nuclear counter stain: DAPI (Blue)
Comment: Color orange is the positive signal for TMAB-03966
Application
Recommended Dose
ICC/IF: 1:100-500; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationMembrane; Single-pass type II membrane protein.
Tissue SpecificityExpressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
ConstructionRecombinant Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Antigen Details
Gene Name
CD38
Gene ID
Protein Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Function
Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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