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Anti-DDR2 Antibody (6A828) is an antibody targeting DDR2. Anti-DDR2 Antibody (6A828) can be used in ELISA, WB, FC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $209 | 7-10 days | |
100 μL | $348 | 7-10 days |
Description | Anti-DDR2 Antibody (6A828) is an antibody targeting DDR2. Anti-DDR2 Antibody (6A828) can be used in ELISA, WB, FC. |
Alias | TYRO10, TKT, NTRKR3, MIG20a, discoidin domain receptor tyrosine kinase 2, CD167 |
Ig Type | Rabbit IgG |
Clone | 6A828 |
Reactivity | Human, Mouse |
Verified Activity | Western Blot -Positive WB detected in: A549 whole cell lysate, SY5Y whole cell lysate, A375 whole cell lysate, HEPG2 whole cell lysate, Mouse Lung tissue lysate -All lanes: DDR2 antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 96 kDa -Observed band size: 110 kDa |
Application | ELISA, WB, FC |
Recommended Dose | WB:1:500-1:2000; FC:1:50-1:200. |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Tyrosine kinase involved in the regulation of tissues remodeling. It functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide: Human DDR2 |
Antigen Species | Human |
Gene ID | 4921 |
Uniprot ID | |
Biology Area | Neuroscience, Cardiovascular |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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