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Anti-SIRT3 Antibody (7T945)
😃Good
Catalog No. TMAB-12816
Anti-SIRT3 Antibody (7T945) is a Rabbit antibody targeting SIRT3. Anti-SIRT3 Antibody (7T945) can be used in WB.
Anti-SIRT3 Antibody (7T945)
Anti-SIRT3 Antibody (7T945)
😃Good
Catalog No. TMAB-12816
Anti-SIRT3 Antibody (7T945) is a Rabbit antibody targeting SIRT3. Anti-SIRT3 Antibody (7T945) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-SIRT3 Antibody (7T945) is a Rabbit antibody targeting SIRT3. Anti-SIRT3 Antibody (7T945) can be used in WB. |
| Ig Type | IgG |
| Clone | 7T945 |
| Reactivity | Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion matrix. |
| Tissue Specificity | Widely expressed. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019] |
| Immunogen | KLH conjugated synthetic peptide: mouse SIRT3 |
| Antigen Species | Mouse |
| Gene Name | SIRT3 |
| Gene ID | |
| Protein Name | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
| Uniprot ID | |
| Function | NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels. |
| Molecular Weight | Theoretical: 43 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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