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Anti-CDH17/Cadherin-17 Antibody (10C12)
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Catalog No. T9901A-821
Anti-CDH17/Cadherin-17 Antibody (10C12) is a recombinant humanized monoclonal antibody targeting Cadherin-17 (CDH17, also known as LI-cadherin). CDH17 is a calcium-dependent cell adhesion protein expressed in normal intestinal epithelium and frequently overexpressed in various gastrointestinal tumors (such as colorectal, gastric, and liver cancers), making it a potential tumor marker.
Anti-CDH17/Cadherin-17 Antibody (10C12)
Anti-CDH17/Cadherin-17 Antibody (10C12)
Copy Product Info😃Good
Catalog No. T9901A-821
Anti-CDH17/Cadherin-17 Antibody (10C12) is a recombinant humanized monoclonal antibody targeting Cadherin-17 (CDH17, also known as LI-cadherin). CDH17 is a calcium-dependent cell adhesion protein expressed in normal intestinal epithelium and frequently overexpressed in various gastrointestinal tumors (such as colorectal, gastric, and liver cancers), making it a potential tumor marker.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-CDH17/Cadherin-17 Antibody (10C12) is a recombinant humanized monoclonal antibody targeting Cadherin-17 (CDH17, also known as LI-cadherin). CDH17 is a calcium-dependent cell adhesion protein expressed in normal intestinal epithelium and frequently overexpressed in various gastrointestinal tumors (such as colorectal, gastric, and liver cancers), making it a potential tumor marker. |
| In vitro | In cell-based assays, Anti-CDH17/Cadherin-17 Antibody (10C12) shows high binding affinity to human CDH17 with an EC50 of approximately 6.722 ng/mL and effectively induces the endocytosis of CDH17 in HEK293 or COLO205 cancer cells [1]. |
| Clone | 10C12 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | CDH17/Cadherin-17 |
| Isotype | IgG1 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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