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Anti-CDH17/Cadherin-17 Antibody (10C12)

Catalog No. T9901A-821 Copy Product Info
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Anti-CDH17/Cadherin-17 Antibody (10C12) is a recombinant humanized monoclonal antibody targeting Cadherin-17 (CDH17, also known as LI-cadherin). CDH17 is a calcium-dependent cell adhesion protein expressed in normal intestinal epithelium and frequently overexpressed in various gastrointestinal tumors (such as colorectal, gastric, and liver cancers), making it a potential tumor marker.

Anti-CDH17/Cadherin-17 Antibody (10C12)

Copy Product Info
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Catalog No. T9901A-821

Anti-CDH17/Cadherin-17 Antibody (10C12) is a recombinant humanized monoclonal antibody targeting Cadherin-17 (CDH17, also known as LI-cadherin). CDH17 is a calcium-dependent cell adhesion protein expressed in normal intestinal epithelium and frequently overexpressed in various gastrointestinal tumors (such as colorectal, gastric, and liver cancers), making it a potential tumor marker.

Anti-CDH17/Cadherin-17 Antibody
(10C12)
Pack SizePriceUSA StockGlobal StockQuantity
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For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CDH17/Cadherin-17 Antibody (10C12) is a recombinant humanized monoclonal antibody targeting Cadherin-17 (CDH17, also known as LI-cadherin). CDH17 is a calcium-dependent cell adhesion protein expressed in normal intestinal epithelium and frequently overexpressed in various gastrointestinal tumors (such as colorectal, gastric, and liver cancers), making it a potential tumor marker.
In vitro
In cell-based assays, Anti-CDH17/Cadherin-17 Antibody (10C12) shows high binding affinity to human CDH17 with an EC50 of approximately 6.722 ng/mL and effectively induces the endocytosis of CDH17 in HEK293 or COLO205 cancer cells [1].
Clone
10C12
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetCDH17/Cadherin-17
Chemical Properties
Antibody Information
IsotypeIgG1
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice.

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