GDF-15 Protein, Human, Recombinant (H202D, hFc)

Name: GDF-15 Protein, Human, Recombinant (H202D, hFc)
Brand: TargetMol
SKU: TMPK-01701
Rating: 4.5 (1 reviews)

(Synonyms: TMPY-04727, TMPY-01073, RG-1, RG1, RG 1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGFBPTGF-b, PTGF-beta, PTGF-b, PTGFB, Placental TGF-β, Placental TGF-beta, Placental TGF-b, PLAB, PDF, NAG-1, NAG1, NAG 1, MIC-1, MIC1, MIC 1, growth differentiation factor 15, GDF-15, GDF15, GDF 15) Copy Product Info

Synonyms: TMPY-04727, TMPY-01073, RG-1, RG1, RG 1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGFBPTGF-b, PTGF-beta, PTGF-b, PTGFB, Placental TGF-β, Placental TGF-beta, Placental TGF-b, PLAB, PDF, NAG-1, NAG1, NAG 1, MIC-1, MIC1, MIC 1, growth differentiation factor 15, GDF-15, GDF15, GDF 15

Catalog No. TMPK-01701 Copy Product Info

GDF-15 Protein, Human, Recombinant (H202D, hFc) is expressed in HEK293 Cells. The accession number is Q99988.

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
5 µg	$81	7-10 days	7-10 days
10 µg	$123	7-10 days	7-10 days
20 µg	$193	7-10 days	7-10 days
50 µg	$348	7-10 days	7-10 days
100 µg	$553	7-10 days	7-10 days
200 µg	$878	7-10 days	7-10 days
500 µg	$1,630	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human GFRAL, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human GDF15 (H202D), hFc Tag with the EC50 of 4.1 ng/ml determined by ELISA.
Description	GDF-15 Protein, Human, Recombinant (H202D, hFc) is expressed in HEK293 Cells. The accession number is Q99988.
Species	Human
Expression System	HEK293 Cells
Tag	N-hFc (IgG1)
Accession Number	Q99988
Construction	Ala197-Ile308 (H202D)
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin	< 1 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	TMPY-04727, TMPY-01073, RG-1, RG1, RG 1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGFBPTGF-b, PTGF-beta, PTGF-b, PTGFB, Placental TGF-β, Placental TGF-beta, Placental TGF-b, PLAB, PDF, NAG-1, NAG1, NAG 1, MIC-1, MIC1, MIC 1, growth differentiation factor 15, GDF-15, GDF15, GDF 15
Research Background	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance.

Chemical Properties

Molecular Weight

37.88 kDa (Predicted); 40-50 kDa (Reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.