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Anti-Midkine Antibody (2L355)

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Catalog No. TMAB-08813

Anti-Midkine Antibody (2L355) is a Rabbit antibody targeting Midkine. Anti-Midkine Antibody (2L355) can be used in ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.

Anti-Midkine Antibody (2L355)

Anti-Midkine Antibody (2L355)

😃Good
Catalog No. TMAB-08813
Anti-Midkine Antibody (2L355) is a Rabbit antibody targeting Midkine. Anti-Midkine Antibody (2L355) can be used in ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Midkine Antibody (2L355) is a Rabbit antibody targeting Midkine. Anti-Midkine Antibody (2L355) can be used in ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.
Ig Type
IgG
Clone
2L355
Reactivity
Human
Application
ICC/IF
IF
IHC-Fr
IHC-P
IP
WB
Recommended Dose
ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; IP=1:20-50; WB=1:1000-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundMidkine, or MK, is a heparin-binding molecule involved in the regulation of growth and differentiation during embryogenesis. MK expression is tightly regulated during embryonic development by steroid receptors of the retinoic acid superfamily. The mature human MK protein is 118 amino acids in length and contains five intrachain disulfide bonds. MK is a non-glycosylated protein that shows greater than 87% identity between human and mouse.
Antigen Details
Immunogen
A synthesized peptide: human Midkine
Antigen Species
Human
Gene Name
MDK
Gene ID
4192
Protein Name
Midkine
Uniprot ID
P21741
Function
Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity).
Chemical Properties
Molecular WeightTheoretical: 16 kDa. Actual: 16 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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