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Anti-Alpha Actinin 2 Antibody (8Z670)

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Catalog No. TMAB-02459

Anti-Alpha Actinin 2 Antibody (8Z670) is a Rabbit antibody targeting Alpha Actinin 2. Anti-Alpha Actinin 2 Antibody (8Z670) can be used in WB,IHC-P,IF,IHC-Fr.

Anti-Alpha Actinin 2 Antibody (8Z670)

Anti-Alpha Actinin 2 Antibody (8Z670)

😃Good
Catalog No. TMAB-02459
Anti-Alpha Actinin 2 Antibody (8Z670) is a Rabbit antibody targeting Alpha Actinin 2. Anti-Alpha Actinin 2 Antibody (8Z670) can be used in WB,IHC-P,IF,IHC-Fr.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Alpha Actinin 2 Antibody (8Z670) is a Rabbit antibody targeting Alpha Actinin 2. Anti-Alpha Actinin 2 Antibody (8Z670) can be used in WB,IHC-P,IF,IHC-Fr.
Ig Type
IgG
Clone
8Z670
Reactivity
Human,Mouse,Rat
Application
WB
IHC-P
IF
IHC-Fr
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IF: 1:50-200; IHC-Fr: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, myofibril, sarcomere, Z line. Note=Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle.
Tissue SpecificityExpressed in both skeletal and cardiac muscle.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
FormulationPBS, Glycerol, BSA.
Concentration1mg/ml
Research BackgroundAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Sarcomeric Alpha Actinin
Antigen Species
Human
Gene Name
ACTN2
Gene ID
88
Protein Name
alpha-actinin-2
Uniprot ID
P35609
Function
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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