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IL-4R Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P24394-1.

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| Biological Activity | Immobilized Human IL-4 R alpha, His Tag at 1 μg/ml (100 μl/Well). Dose response curve for Biotinylated Human IL-4, His Tag with the EC50 of 6.1 ng/ml determined by ELISA. |
| Description | IL-4R Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P24394-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | P24394-1 |
| Synonyms | interleukin 4 receptor,IL-4RA,IL4RA,IL4R,CD124 |
| Construction | Gly24-His232 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Molecular Weight | 24.7 kDa (Predicted); 45-70 kDa (Due to glycosylation) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family.The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells. |
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