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CDKN2A/p16INK4a Protein, Human, Recombinant (GST)
(Synonyms: p16INK4A, p16-INK4, MTS-1, MTS1, Cyclin-dependent kinase inhibitor 2A, CDKN2A, CDKN2, CDK4I) Copy Product InfoSynonyms: p16INK4A, p16-INK4, MTS-1, MTS1, Cyclin-dependent kinase inhibitor 2A, CDKN2A, CDKN2, CDK4I
Catalog No. TMPC-00149 Copy Product Info
CDKN2A/p16INK4a Protein, Human, Recombinant (GST) is expressed in E. coli. The accession number is P42771.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μg | $987 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | CDKN2A/p16INK4a Protein, Human, Recombinant (GST) is expressed in E. coli. The accession number is P42771. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-GST |
| Accession Number | P42771 |
| Construction | Recombinant full length human p16INK4A was expressed in E. coli cells using a N-terminal GST tag. |
| Protein Purity | >70% as determined by SDS-PAGE.  |
| Formulation | Supplied as sterile 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products. |
| Synonyms | p16INK4A, p16-INK4, MTS-1, MTS1, Cyclin-dependent kinase inhibitor 2A, CDKN2A, CDKN2, CDK4I |
| Research Background | CDKN2A germline mutations increase the risk of melanoma development. CDKN2A/CDK4 were the first high-penetrance melanoma genes identified. CDKN2A suppresses the initiation of melanoma invasion through inhibition of BRN2. It's a potential prognostic role of CDKN2A/B deletions in early disease stratification in pediatric B-ALL. CDKN2A coding region germline variants are associated with pancreatic adenocarcinoma (PC) susceptibility. |
| Molecular Weight | ~41 kDa |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: CDKN2A/p16INK4a Protein, Human, Recombinant (GST) chemical structure | CDKN2A/p16INK4a Protein, Human, Recombinant (GST) molecular weight
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